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RE: microbiology

Contribution from Bernd Renger written on 6/30/2008 at 09:49

Original contribution: microbiology written by gagandeep kaur on 6/28/2008 at 06:16)

USP and EP require suitablity tests for media used for sterility testing. They are performed before or in parallel with the test. These suitablity tests include a growth promotion test using defined strains and a test for sterility (incubation at defined temperature for 14 days).

For total viable count testing a growth promotion test must be performed. A test for sterility is not mentioned. If a preincubation of the plates for 48 hours is performed it might be better to do the growth promotion test after this preincubation.

Best regards, Bernd Renger

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